88032772 at around 31:15 match timer, I had 4 active items and used my golden goose egg to free up my 4th slot. I bought scourge to be my 4th active, but instead of using the empty slot at the end it overrode the guardian ward I had in my second slot. And then a few seconds later, when I upgrade guardian ward to divine barrier, scourge then gets replaced by that. After that, I was unable to use scourge (it didnt even show up when hovering teammates) and moving around my 3-4 slot actives didn’t fix the issue (though the overridden active was in slot 2).
I had a similar bug in match 88234172, starting at about 32:13. My cursed relic remained unusable for the rest of the match.
I wanted to buy Cursed Relic, but I had Divine Barrier on the auto-buy queue. (I already had Guardian Ward)
When I dropped into the shop, it automatically upgraded my Guardian Ward to Divine Barrier. I then sold Divine Barrier, which reverted it to Guardian Ward and gave me my money back, but when I then purchased Cursed Relic, it was placed in the slot where Guardian Ward was. (On my end, it looked like Guardian Ward was not on my active items bar, but I could see that I’d purchased it.) Then, when I pressed “Z” (the key associated with Guardian Ward and Cursed Relic, the selection hud for Cursed Relic would appear for a split second, then vanish. I couldn’t cast the spell on anyone.
I tried a couple things to fix it, including selling the Guardian Ward, moving the position of the active items on my bar, disconnecting and reconnecting, etc. during the match but nothing fixed it.
Edit: I don’t imagine this was related, but I was playing Rem, same as the above poster.